“Those individuals should be appropriately hydrated to decrease the plasma viscosity, they should receive high-intensity glucocorticoids to decrease the inflammatory response, and they should be monitored much more closely because of the prognostic significance of an elevated blood viscosity,” he advised. “If you have elevated blood viscosity, high shear or low shear, those individuals are in an accelerated pathway for death,” senior author Robert Rosenson, MD (Icahn School of Medicine at Mount Sinai, New York, NY), told TCTMD, noting that the relationship held true even after adjustment for many of the biomarkers that have been used to stratify risk in the setting of COVID-19. The risk of in-hospital all-cause mortality increased along with rising estimates of blood viscosity, with patients with the highest estimates of high-shear and low-shear blood viscosity having 53% and 36% greater relative risks, respectively, compared with their counterparts with the least-viscous blood. More-viscous blood, which increases the propensity for clotting, is a sign that patients hospitalized for COVID-19 are more likely to do worse over the short term, according to data from a New York City health system.
0 kommentar(er)
